Open AccessPolymorphism and expression of the Dvl3 gene in the etiology of depressive disorder
Author(s) -
Marlena Zajączkowska,
Monika Talarowska,
Janusz Szemraj,
Piotr Gałecki
Publication year - 2020
Publication title -
psychiatria polska
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.414
H-Index - 22
eISSN - 2391-5854
pISSN - 0033-2674
DOI - 10.12740/pp/103853
Subject(s) - locus (genetics) , chemistry , microbiology and biotechnology , gene , medicine , genetics , biology
The aim of this study was to investigate the role of the Dvl3 gene in the etiology of depression by comparison of Dvl3 mRNA expression, Dvl3 protein levels and polymorphism at locus rs1969253 located in the intron of the Dvl3 gene in patients suffering from depression versus healthy controls, as well as to search for clinical variables related to polymorphism or expression of the analyzed gene.
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