Precursor-Directed Biosynthesis of Curcumin Analogs inEscherichia coli | Zendy

Yohei Katsuyama | Zendy; Yutaka Hirose | Zendy; Nobutaka Funa | Zendy; Yasuo Ohnishi | Zendy; Sueharu Horinouchi | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Precursor-Directed Biosynthesis of Curcumin Analogs inEscherichia coli

Author(s) -

Yohei Katsuyama,

Yutaka Hirose,

Nobutaka Funa,

Yasuo Ohnishi,

Sueharu Horinouchi

Publication year - 2010

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.90866

Subject(s) - curcuminoid , curcumin , escherichia coli , biosynthesis , chemistry , rhizome , biochemistry , escherichia , biology , enzyme , gene , ecology

Curcuminoids, natural products in the rhizome of turmeric, show various biological activities, including antioxidant and antitumor activities. For this reason, curcuminoids have been focused on as potential pharmaceuticals. Exogenous supplementation with various carboxylate precursors in genetically engineered Escherichia coli cells carrying an artificially assembled pathway for curcuminoid biosynthesis led to the production of 17 unnatural curcuminoids.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research