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Cellulase Hyperproducing Mutants Derived from the FungusTrichoderma reeseiQM9414 Produced Large Amounts of Cellulase at the Enzymatic and Transcriptional Levels
Author(s) -
Tatsuya Fujii,
Katsuji Murakami,
Shigeki Sawayama
Publication year - 2010
Publication title -
bioscience biotechnology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.509
H-Index - 116
eISSN - 1347-6947
pISSN - 0916-8451
DOI - 10.1271/bbb.90655
Subject(s) - cellulase , trichoderma reesei , mutant , fungus , enzyme , transcription (linguistics) , microbiology and biotechnology , filter paper , wild type , biochemistry , gene , biology , chemistry , botany , chromatography , linguistics , philosophy
Cellulase hyperproducing mutants derived from the fungus Trichoderma reesei QM9414 were analyzed. They exhibited higher filter-paper degrading activity and a lower growth rate than the wild-type QM9414 strain. Transcription of the cellobiohydrolase I and endoglucanase I genes in the mutants was also greater than that of QM9414, suggesting that cellulase hyperproduction by these mutants was regulated at the transcriptional level.

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