Diverse Immune Responses to Orally Administered Heat-Killed Cell Preparation ofEnterococcus faecalisStrain EC-12 in Murine Immune Tissues | Zendy

Tohru Yoshikawa | Zendy; Ryo Inoüe | Zendy; Yoko Yoshida | Zendy; T Watanabe | Zendy; Wakoto Bukawa | Zendy; Kazunari Ushida | Zendy

Open Access

Diverse Immune Responses to Orally Administered Heat-Killed Cell Preparation ofEnterococcus faecalisStrain EC-12 in Murine Immune Tissues

Author(s) -

Tohru Yoshikawa,

Ryo Inoüe,

Yoko Yoshida,

T Watanabe,

Wakoto Bukawa,

Kazunari Ushida

Publication year - 2009

Publication title -

bioscience biotechnology and biochemistry

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.90010

Subject(s) - immune system , mesenteric lymph nodes , spleen , lymph , microbiology and biotechnology , jejunum , immunology , biology , bacteria , enterococcus faecalis , peyer's patch , ileum , medicine , pathology , endocrinology , genetics , staphylococcus aureus

Diverse immune responses to an orally administered heat-killed cell preparation of Enterococcus faecalis strain EC-12 (EC-12) among jejunal-Peyer's patches (PPs), ileal-PPs, mesenteric lymph nodes (MLNs), and spleen were compared by real-time PCR in mice. Intriguingly, distinct responses to EC-12 were observed in the various tissues. This study indicates a site-specific response to orally administered bacteria, particularly in jejunal- and ileal-PPs.

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