Inhibition of Pathogen Adhesion to Host Cells by Polysaccharides fromPanax ginseng | Zendy

Ji Hye Lee | Zendy; Jin Sun Shim | Zendy; Mi Sook Chung | Zendy; Seung-Taik Lim | Zendy; Kyung Hyun Kim | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Inhibition of Pathogen Adhesion to Host Cells by Polysaccharides fromPanax ginseng

Author(s) -

Ji Hye Lee,

Jin Sun Shim,

Mi Sook Chung,

Seung-Taik Lim,

Kyung Hyun Kim

Publication year - 2009

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.80555

Subject(s) - ginseng , arabinogalactan , polysaccharide , pathogen , adhesion , microbiology and biotechnology , pectin , chemistry , hydrolysis , bacteria , adhesive , enzymatic hydrolysis , host (biology) , traditional medicine , biology , biochemistry , medicine , organic chemistry , genetics , alternative medicine , pathology , layer (electronics) , ecology

PG-F2 and PG-HMW from Panax ginseng are pectin-type polysaccharides and PG-HMW might be an arabinogalactan. They demonstrated strong anti-adhesive activities against oral and skin pathogens to host cell lines in a dose-dependent manner from 0.1 to 2.0 mg/ml. While enzymatic hydrolysis caused complete loss of anti-adhesive activities, partial hydrolysis produced oligosaccharides with anti-adhesive properties. PG-F2 and PG-HMW might have a selective anti-adhesive effect against certain pathogenic bacteria without adverse effects on commensal bacteria.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research