Disruption of theSCS2Ortholog in the Alkane-Assimilating YeastYarrowia lipolyticaImpairs Its Growth onn-Decane, but Does Not Impair Inositol Prototrophy | Zendy

Satoshi Kobayashi | Zendy; Kiyoshi Hirakawa | Zendy; Ryouichi Fukuda | Zendy; Akinori Ohta | Zendy

Open Access

Disruption of theSCS2Ortholog in the Alkane-Assimilating YeastYarrowia lipolyticaImpairs Its Growth onn-Decane, but Does Not Impair Inositol Prototrophy

Author(s) -

Satoshi Kobayashi,

Kiyoshi Hirakawa,

Ryouichi Fukuda,

Akinori Ohta

Publication year - 2008

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.80230

Subject(s) - yarrowia , auxotrophy , yeast , decane , saccharomyces cerevisiae , gene , biochemistry , biology , alkane , inositol , function (biology) , chemistry , genetics , escherichia coli , receptor , organic chemistry , catalysis

Disruption of an SCS2 ortholog impaired the growth of the alkane-assimilating yeast Yarrowia lipolytica on n-alkanes, particularly on n-decane, although the mRNA level of the ALK1 gene encoding a highly inducible cytochrome P450ALK was not much affected. The same disruption did not cause inositol auxotrophy, implying that Y. lipolytica SCS2 has a different function from its Saccharomyces cerevisiae counterpart.

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