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A Comparison of the Unfolded Protein Response in Solid-State with Submerged Cultures ofAspergillus oryzae
Author(s) -
Lei Ye,
Li Pan
Publication year - 2008
Publication title -
bioscience biotechnology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.509
H-Index - 116
eISSN - 1347-6947
pISSN - 0916-8451
DOI - 10.1271/bbb.80146
Subject(s) - aspergillus oryzae , unfolded protein response , homeostasis , heat shock protein , mechanism (biology) , fight or flight response , shock (circulatory) , microbiology and biotechnology , biology , endoplasmic reticulum , gene , genetics , biochemistry , enzyme , physics , medicine , quantum mechanics
The unfolded protein response (UPR) is a regulatory system to maintain the homeostasis of ER functions. Here we report a comparison of express levels of UPR relevant genes in Aspergillus oryzae between solid-state and submerged cultivation. The results were that up-regulation of the UPR mechanism in solid-state culture was higher than in submerged culture (heat-shock or non-stress conditions). This might have been a result of changing culture conditions.

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