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Effect of Dietary Soybean Protein Level on the Plasma Homocysteine Concentration in Rats
Author(s) -
Hiroshi OKAWA,
Tatsuya Morita,
Kimio SUGIYAMA
Publication year - 2008
Publication title -
bioscience biotechnology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.509
H-Index - 116
eISSN - 1347-6947
pISSN - 0916-8451
DOI - 10.1271/bbb.70797
Subject(s) - homocysteine , plasma homocysteine , cystathionine beta synthase , dietary protein , chemistry , medicine , endocrinology , soy protein , food science , biochemistry , methionine , biology , amino acid
There was an inverse correlation between the plasma homocysteine concentration and dietary protein level or protein intake when a soybean protein isolate (SPI) was used as a protein source for rats. The hepatic cystathionine beta-synthase activity increased in response to the dietary SPI level. The results suggest that a high-protein diet might be an effective means to lower the plasma homocysteine concentration, probably through enhancement of the homocysteine-metabolizing activity.

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