Interaction of Tea Catechins with Lipid Bilayers Investigated by a Quartz-Crystal Microbalance Analysis | Zendy

Miya Kamihira | Zendy; Hiromi Nakazawa | Zendy; Atsushi Kira | Zendy; Yumi Mizutani | Zendy; Mikihiko Nakamura | Zendy; Tsutomu Nakayama | Zendy

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Interaction of Tea Catechins with Lipid Bilayers Investigated by a Quartz-Crystal Microbalance Analysis

Author(s) -

Miya Kamihira,

Hiromi Nakazawa,

Atsushi Kira,

Yumi Mizutani,

Mikihiko Nakamura,

Tsutomu Nakayama

Publication year - 2008

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.70786

Subject(s) - quartz crystal microbalance , chemistry , epigallocatechin gallate , gallate , lipid bilayer , epicatechin gallate , catechin , analytical chemistry (journal) , chromatography , crystallography , polyphenol , organic chemistry , membrane , nuclear chemistry , biochemistry , adsorption , antioxidant

The quartz-crystal microbalance (QCM) technique was applied to investigate the interaction of tea catechins with lipid bilayers. The association constants obtained from the frequency changes of QCM revealed that (-)epicatechin gallate and (-)epigallocatechin gallate interacted with 1,2-dimyristoyl-sn-glycero-3-phosphocholine ca. 1000 times more strongly than (-)epicatechin and (-)epigallocatechin. The results exhibited good correlation with the strength of biological activity.

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