Dillapiol and Apiol as Specific Inhibitors of the Biosynthesis of Aflatoxin G1inAspergillus parasiticus | Zendy

Mehdi RazzaghiAbyaneh | Zendy; Tomoya Yoshinari | Zendy; Masoomeh ShamsGhahfarokhi | Zendy; Mohammad-Bagher Rezaee | Zendy; Hiromichi Nagasawa | Zendy; Shohei Sakuda | Zendy

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Dillapiol and Apiol as Specific Inhibitors of the Biosynthesis of Aflatoxin G₁inAspergillus parasiticus

Author(s) -

Mehdi RazzaghiAbyaneh,

Tomoya Yoshinari,

Masoomeh ShamsGhahfarokhi,

Mohammad-Bagher Rezaee,

Hiromichi Nagasawa,

Shohei Sakuda

Publication year - 2007

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.70264

Subject(s) - aspergillus parasiticus , aflatoxin , aspergillus , ic50 , food science , mycotoxin , fungal growth , chemistry , biosynthesis , biology , biochemistry , microbiology and biotechnology , in vitro , enzyme

Dillapiol was isolated from the essential oil of dill as a specific inhibitor of aflatoxin G1 production. It inhibited aflatoxin G1 production by Aspergillus parasiticus with an IC50 value of 0.15 microM without inhibiting aflatoxin B1 production or fungal growth. Apiol and myristicin, congeners of dillapiol, showed similar activity with IC50 values of 0.24 and 3.5 microM, respectively.

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