Regulation of the Body Fat Percentage in Developmental-Stage Rats by Methylxanthine Derivatives in a High-Fat Diet | Zendy

Hiroko Inoue | Zendy; Kazuo Kobayashi | Zendy; Yumi Horiuchi | Zendy; Yuichi Oishi | Zendy; Souichi ARAI | Zendy; Toshichika Takita | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Regulation of the Body Fat Percentage in Developmental-Stage Rats by Methylxanthine Derivatives in a High-Fat Diet

Author(s) -

Hiroko Inoue,

Kazuo Kobayashi,

Yumi Horiuchi,

Yuichi Oishi,

Souichi ARAI,

Toshichika Takita

Publication year - 2006

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.70.1134

Subject(s) - caffeine , theophylline , theobromine , adipose tissue , endocrinology , medicine , triglyceride , abdominal fat , adipocyte , body weight , chemistry , cholesterol

We investigated the regulatory effects of structural differences among methylxanthine derivatives on the elevation of body fat percentage in developmental-stage rats. Caffeine, theophylline and theobromine were used as the methylxanthines. High-fat diets (20% lard) containing each methylxanthine (0.025%) were administered to male Sprague-Dawley rats for 12 weeks, with the result that the body fat percentage was generally reduced in each methylxanthine-fed group. The abdominal adipose tissue weight in the caffeine group was also significantly lower than that in the control group, the serum cholesterol and triglyceride levels in the caffeine group also being significantly lower than the levels in the control group. The study results suggest that caffeine could contribute most to preventing arteriosclerotic diseases.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research