Biosynthesis of the Marine Antibiotic Pentabromopseudilin. 2. The Pyrrole Ring | Zendy

Jörg D. PESCHKE | Zendy; Ulf Hanefeld | Zendy; Hartmut Laatsch | Zendy

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Biosynthesis of the Marine Antibiotic Pentabromopseudilin. 2. The Pyrrole Ring

Author(s) -

Jörg D. PESCHKE,

Ulf Hanefeld,

Hartmut Laatsch

Publication year - 2005

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.69.628

Subject(s) - alteromonas , pyrrole , biosynthesis , proline , ring (chemistry) , antibiotics , chemistry , biochemistry , stereochemistry , bacteria , microbiology and biotechnology , biology , amino acid , organic chemistry , enzyme , genetics

The biosynthesis of the potent marine antibiotic, pentabromopseudilin (1), was investigated. Feeding studies with Alteromonas luteoviolaceus were performed on a defined medium. D,L-[5-(13)C]proline was incorporated symmetrically, demonstrating that the pyrrole ring of pentabromopseudilin is derived from proline.

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