Sericin Enhances Attachment of Cultured Human Skin Fibroblasts | Zendy

Kozo Tsubouchi | Zendy; Yumiko Igarashi | Zendy; Yoko Takasu | Zendy; Hiromi Yamada | Zendy

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Sericin Enhances Attachment of Cultured Human Skin Fibroblasts

Author(s) -

Kozo Tsubouchi,

Yumiko Igarashi,

Yoko Takasu,

Hiromi Yamada

Publication year - 2005

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.69.403

Subject(s) - sericin , human skin , fibroblast , chemistry , microbiology and biotechnology , serine , biophysics , silk , biochemistry , materials science , biology , in vitro , enzyme , composite material , genetics

Human skin fibroblasts were cultured on sericin prepared from cocoon shells. The living cell number after 72 h was enhanced to 250% of the no-sericin control. The increase was due to the acceleration of the initial attachment of the cells. It was found that sericin M, the main component of about 400 kDa, and its serine-rich repetitive domain were the active principles.

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