Penipratynolene, a Novel Nematicide fromPenicillium bilaiaeChalabuda | Zendy

Satoshi Nakahara | Zendy; Miyako Kusano | Zendy; Shozo Fujioka | Zendy; Atsumi Shimada | Zendy; Yasuo Kimura | Zendy

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Penipratynolene, a Novel Nematicide fromPenicillium bilaiaeChalabuda

Author(s) -

Satoshi Nakahara,

Miyako Kusano,

Shozo Fujioka,

Atsumi Shimada,

Yasuo Kimura

Publication year - 2004

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.68.257

Subject(s) - bioassay , penicillium , nematode , pratylenchus penetrans , biology , stereochemistry , chemistry , botany , ecology

New acetylenic nematicidal compound, penipratynolene (1), methy (2'R)-4-(2'-hydroxy-3'-butynoxy)benzoate, together with two known compounds, 6-methoxycarbonylpicolinic acid (2) and 2,6-pyridinedicarboxylic acid (3), were isolated from the culture filtrate of Penicillium bilaiae Chalabuda. The structures of 1-3 were established by spectroscopic methods. The absolute configuration of 1 was confirmed by using a modified version of Mosher's method. Compounds 1-3 showed nematicidal activity of 77%, 52%, and 98%, respectively, by a bioassay at 300 mg/l with the root-lesion nematode Pratylenchus penetrans.

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