Erinacol (Cyatha-3,12-dien-14β-ol) and 11-O-Acetylcyathin A3, New Cyathane Metabolites from an Erinacine Q-ProducingHericium erinaceum
Author(s) -
Hiromichi Kenmoku,
Kazumi Tanaka,
Katsuhide Okada,
Nobuo Kato,
Takeshi Sassa
Publication year - 2004
Publication title -
bioscience biotechnology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.509
H-Index - 116
eISSN - 1347-6947
pISSN - 0916-8451
DOI - 10.1271/bbb.68.1786
Subject(s) - metabolite , mycelium , stereochemistry , biosynthesis , chemistry , spectral analysis , biochemistry , biology , botany , physics , gene , spectroscopy , quantum mechanics
In our search for new cyathane metabolites related to the biosynthesis of erinacine Q in Hericium erinaceum, we isolated a novel cyatha-3,12-dien-14beta-ol named erinacol together with known 11-O-acetylcyathatriol (the erinacine Q aglycon) and new metabolite 11-O-acetylcyathin A(3) from the mycelial extract. The structure of each compound was determined by spectral methods. Possible biosynthetic relationships of these metabolites are discussed from their structural features.
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