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Independent use of K(2) and D(3) and simultaneous application of K(2) and D(3) inhibited the development of osteoporosis caused by PD food intake. The ALP activity of urine as a marker of bone formation osteoporosis did not rise in rats fed PD foods containing D(3), K(2) or both together. Body and womb weights fell in rats fed PD foods with D(3) K(2) and both D(3), K(2). Osteoporosis caused by PD food intake found to be very similar to type II osteoporosis in respects of inhibition by D(3) and K(2) and rising urinary ALP activity.

Inhibition of Osteoporosis Induced by Protein Deficient (PD) Food Intake by Active Vitamin D3and Vitamin K2in Rats

Inhibition of Osteoporosis Induced by Protein Deficient (PD) Food Intake by Active Vitamin D₃and Vitamin K₂in Rats