Inhibition of Osteoporosis Induced by Protein Deficient (PD) Food Intake by Active Vitamin D3and Vitamin K2in Rats | Zendy

Liman Sun | Zendy; Hajime Tamaki | Zendy; Yutaka Ohta | Zendy; Naofumi Katsuyama | Zendy; Tetsuji ISHIMARU | Zendy; Isao Chinen | Zendy

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Inhibition of Osteoporosis Induced by Protein Deficient (PD) Food Intake by Active Vitamin D₃and Vitamin K₂in Rats

Author(s) -

Liman Sun,

Hajime Tamaki,

Yutaka Ohta,

Naofumi Katsuyama,

Tetsuji ISHIMARU,

Isao Chinen

Publication year - 2004

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.68.1385

Subject(s) - osteoporosis , medicine , endocrinology , vitamin d and neurology , urine , vitamin , urinary system , chemistry , food intake

Independent use of K(2) and D(3) and simultaneous application of K(2) and D(3) inhibited the development of osteoporosis caused by PD food intake. The ALP activity of urine as a marker of bone formation osteoporosis did not rise in rats fed PD foods containing D(3), K(2) or both together. Body and womb weights fell in rats fed PD foods with D(3) K(2) and both D(3), K(2). Osteoporosis caused by PD food intake found to be very similar to type II osteoporosis in respects of inhibition by D(3) and K(2) and rising urinary ALP activity.

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