Microbial Hydroxylation of Indole to 7-Hydroxyindole byAcinetobacter calcoaceticusStrain 4-1-5 | Zendy

Daisuke Sugimori | Zendy; Takanori Sekiguchi | Zendy; Fumihiko Hasumi | Zendy; Motoki Kubo | Zendy; Naoki Shirasaka | Zendy; Masaya Ikunaka | Zendy

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Microbial Hydroxylation of Indole to 7-Hydroxyindole byAcinetobacter calcoaceticusStrain 4-1-5

Author(s) -

Daisuke Sugimori,

Takanori Sekiguchi,

Fumihiko Hasumi,

Motoki Kubo,

Naoki Shirasaka,

Masaya Ikunaka

Publication year - 2004

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.68.1167

Subject(s) - indole test , strain (injury) , hydroxylation , cometabolism , chemistry , acinetobacter calcoaceticus , carbon source , cofactor , stereochemistry , microbiology and biotechnology , organic chemistry , bacteria , biochemistry , biology , acinetobacter , enzyme , bioremediation , genetics , anatomy , antibiotics

A screening study yielded Acinetobacter calcoaceticus strain 4-1-5, which is capable of hydroxylating indole to 7-hydroxyindole. Strain 4-1-5 grew on terephthalate as the sole source of carbon and energy and hydroxylated indole to 7-hydroxyindole by cometabolism of indole using terephthalate as cosubstrate. Strain 4-1-5 produced 0.574 mM of 7-hydroxyindole at 2.38 mM indole in 24 h with the cell growth.

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