Tocotrienol Levels in Various Tissues of Sprague-Dawley Rats after Intragastric Administration of Tocotrienols | Zendy

Masaaki Okabe | Zendy; Mariko Oji | Zendy; Ikuo Ikeda | Zendy; Hirofumi Tachibana | Zendy; Kôji Yamada | Zendy

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Tocotrienol Levels in Various Tissues of Sprague-Dawley Rats after Intragastric Administration of Tocotrienols

Author(s) -

Masaaki Okabe,

Mariko Oji,

Ikuo Ikeda,

Hirofumi Tachibana,

Kôji Yamada

Publication year - 2002

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.66.1768

Subject(s) - adipose tissue , spleen , endocrinology , medicine , tocotrienol , kidney , distribution (mathematics) , chemistry , tocopherol , vitamin e , antioxidant , mathematical analysis , biochemistry , mathematics

A tocotrienol (T3) mixture was intragastricaly administered to Sprague-Dawley rats, and the T3 levels in various tissues were measured 0, 4, 8 and 24 hr after the administration. In blood clots, brain, thymus, testes, vice-testes and muscles, T3 homologues were not detected at all. In epididymal adipose, renal adipose, subcutaneous adipose and brown adipose tissues and in the heart, the T3 levels were maintained or increased for 24 hr after the administration. In the serum, liver, mesenteric lymph node, spleen and lungs, the T3 levels were highest 8 hr after the T3 administration. These results suggest that the distribution and metabolism of T3 in the rat vary considerably among different tissues.

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