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Chemical derivation methods were used to prepare milbemycins beta9 and beta10 from milbemycins A3 and A4. Their acaricidal activities were also assessed against the organophosphorus-sensitive two-spotted spider mite (Tetranychus urticae) on primary leaves of cowpea plants (Vigna sinesis Savi species) by spraying.

Synthesis of Milbemycins β9and β10from Milbemycins A3and A4and Their Biological Activities

Synthesis of Milbemycins β₉and β₁₀from Milbemycins A₃and A₄and Their Biological Activities