Open AccessEnantioselective Hydrolysis ofo-Nitrostyrene Oxide by Whole Cells ofAspergillus nigerCGMCC 0496
Author(s) -
Hao Jin,
ZuYi Li
Publication year - 2002
Publication title -
bioscience biotechnology and biochemistry
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.509
H-Index - 116
eISSN - 1347-6947
pISSN - 0916-8451
DOI - 10.1271/bbb.66.1123
Subject(s) - aspergillus niger , epoxide , substrate (aquarium) , hydrolysis , chemistry , nuclear chemistry , biochemistry , biology , catalysis , ecology
The asymmetric biohydrolysis is described of o-nitrostyrene oxide with high selectivity by whole cells of Aspergillus niger CGMCC 0496. Both the epoxide and diol could be obtained in a high state of optical purity (over 98%). Product inhibition was found when using a high ratio of substrate to cells.
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