Unique Occurrence of the 1CF11 Carbohydrate Epitope in Primate Saliva
Author(s) -
Shan-Ming Yang,
Naoko YOKOI,
Yoshihiro Kanamaru,
Osamu Takenaka,
Yasuro Atoji,
Yasuo Bunai,
Isao Ohya,
Xong-Guang SONG,
Satoshi Nagaoka,
Makoto Shimizu,
Goverdhan P. Sachdev
Publication year - 2001
Publication title -
bioscience biotechnology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.509
H-Index - 116
eISSN - 1347-6947
pISSN - 0916-8451
DOI - 10.1271/bbb.65.714
Subject(s) - saliva , epitope , mucin , monoclonal antibody , glycoprotein , biology , antigen , antibody , primate , carbohydrate , immunology , microbiology and biotechnology , biochemistry , neuroscience
We examined a large number of individual human and animal saliva samples for the reactivity with ICF11, a mouse monoclonal antibody previously produced for the characterization of human milk mucin and apparently recognizing a certain carbohydrate antigenic structure shared by various human glycoproteins in secretions. The results obtained here confirm the unique occurrence of ICF11 epitope in each and every saliva sample from humans and Old world monkeys as well, though a vast variety was observed among individual saliva samples in the immunological reactivity with ICF11.
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