Structure Elucidation of Ostreocin D, a Palytoxin Analog Isolated from the Dinoflagellate Ostreopsis siamensis | Zendy

Takanori Ukena | Zendy; Masayuki Satake | Zendy; Masaya Usami | Zendy; Yasukatsu Oshima | Zendy; Hideo Naoki | Zendy; Tsuyoshi Fujita | Zendy; Yukiko Kan | Zendy; Takeshi Yasumoto | Zendy

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Structure Elucidation of Ostreocin D, a Palytoxin Analog Isolated from the Dinoflagellate Ostreopsis siamensis

Author(s) -

Takanori Ukena,

Masayuki Satake,

Masaya Usami,

Yasukatsu Oshima,

Hideo Naoki,

Tsuyoshi Fujita,

Yukiko Kan,

Takeshi Yasumoto

Publication year - 2001

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.65.2585

Subject(s) - palytoxin , dinoflagellate , stereochemistry , chemistry , botany , biology , biochemistry , toxin

The structure of ostreocin D, a palytoxin analog isolated from the marine dinoflagellate Ostreopsis siamensis, was found to be 42-hydroxy-3,26-didemethyl-19,44-dideoxypalytoxin by detailed 2D NMR analyses of intact ostreocin D and its ozonolysis products. Partial stereochemical assignments were done. This result indicates that the dinoflagellate O. siamensis is one of the biogenetic origins of palytoxin.

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