Analysis of the Isoform of Xenopus Euakryotic Translation Initiation Factor 4E
Author(s) -
Motoaki Wakiyama,
Aki SUZUKI,
Motoki Saigoh,
Nobuya Sakai,
Hiroshi Miyoshi,
Shuichi Kojima,
Kinichiro Miura
Publication year - 2001
Publication title -
bioscience biotechnology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.509
H-Index - 116
eISSN - 1347-6947
pISSN - 0916-8451
DOI - 10.1271/bbb.65.232
Subject(s) - xenopus , eif4e , gene isoform , translation (biology) , initiation factor , eukaryotic translation , eukaryotic translation initiation factor 4 gamma , eif4a1 , microbiology and biotechnology , biology , protein biosynthesis , eukaryotic initiation factor , messenger rna , genetics , gene
We have found two isoforms of the eukaryotic translation initiation factor 4E (eIF4E) in Xenopus laevis. These proteins differ in length by 18 amino acids. Overexpression of either of the two eIF4E proteins modestly increase translation in Xenopus oocytes. The results suggest that both of these two isoforms function in translation.
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