Inhibition by Agaricus blazei Murill Fractions of Cytopathic Effect Induced by Western Equine Encephalitis (WEE) Virus on VERO Cells in Vitro | Zendy

Kenji Sorimachi | Zendy; Yukari Ikehara | Zendy; Genzo MAEZATO | Zendy; Akira Ōkubo | Zendy; Sunao Yamazaki | Zendy; Kazumi Akimoto | Zendy; Akira Niwa | Zendy

Open Access

Inhibition by Agaricus blazei Murill Fractions of Cytopathic Effect Induced by Western Equine Encephalitis (WEE) Virus on VERO Cells in Vitro

Author(s) -

Kenji Sorimachi,

Yukari Ikehara,

Genzo MAEZATO,

Akira Ōkubo,

Sunao Yamazaki,

Kazumi Akimoto,

Akira Niwa

Publication year - 2001

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.65.1645

Subject(s) - vero cell , mycelium , cytopathic effect , in vitro , virus , microbiology and biotechnology , encephalitis , ethanol , chemistry , virology , biology , biochemistry , botany

Anti-viral activities of Agaricus blazei Murill were investigated. The water extracts of the cultured mycelia and fruiting bodies were fractionated with different concentrations of ethanol. To several viruses which have cytopathic effects (CPE) on VERO cells, inhibition of these effects by the ethanol fractions was tested. Strong inhibition of CPE induced by western equine encephalitis (WEE) virus was observed in the mycelial fractions but not those of fruiting bodies.

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