Steroid 5α-Reductase Inhibitory Activity and Hair Regrowth Effects of an Extract fromBoehmeria nipononivea | Zendy

Kuniyoshi Shimizu | Zendy; Ryuichiro Kondo | Zendy; Kokki Sakai | Zendy; Yoshihiro Shoyama | Zendy; H. Sato | Zendy; Tetsuya Ueno | Zendy

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Steroid 5α-Reductase Inhibitory Activity and Hair Regrowth Effects of an Extract fromBoehmeria nipononivea

Author(s) -

Kuniyoshi Shimizu,

Ryuichiro Kondo,

Kokki Sakai,

Yoshihiro Shoyama,

H. Sato,

Tetsuya Ueno

Publication year - 2000

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.64.875

Subject(s) - chemistry , elaidic acid , inhibitory postsynaptic potential , stearic acid , biochemistry , linoleic acid , biology , fatty acid , organic chemistry , endocrinology

The acetone extract of Boehmeria nipononivea showed both potent 5alpha-reductase inhibitory activity and hair regrowth promotion effects on mice. 5alpha-Reductase inhibitory activity-guided fractionation led to six active fatty acids: alpha-linolenic, linoleic, palmitic, elaidic, oleic and stearic acids. The extract of B. nipononivea, and alphalinolenic, elaidic and stearic acids exhibited a hair regrowth effect.

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