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Effect of a Polysaccharide (TAP) from the Fruiting Bodies ofTremella aurantiaon Glucose Metabolism in Mouse Liver
Author(s) -
Tadashi Kiho,
Hotaka MORIMOTO,
Takashi Kobayashi,
Shigeyuki Usui,
Shigeo Ukai,
Koichi Aizawa,
Takahiro Inakuma
Publication year - 2000
Publication title -
bioscience biotechnology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.509
H-Index - 116
eISSN - 1347-6947
pISSN - 0916-8451
DOI - 10.1271/bbb.64.417
Subject(s) - glycogen , hexokinase , polysaccharide , glucokinase , tap water , carbohydrate metabolism , alkaline phosphatase , chemistry , endocrinology , biochemistry , metabolism , enzyme , medicine , biology , glycolysis , engineering , environmental engineering
An acidic polysaccharide (TAP) obtained from the fruiting bodies of Tremella aurantia significantly increased the activities of glucokinase, hexokinase, and glucose-6-phosphate dehydrogenase, and decreased the activity of glucose-6-phosphatase in normal and diabetic mouse liver after intraperitoneal administration, while the glycogen content in the liver was reduced. Furthermore, TAP lowered the plasma cholesterol level in normal and diabetic mice.

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