Enzymatic Preparation of Genuine Prosapogenin, 20(S)-Ginsenoside Rh1, from Ginsenosides Re and Rg1 | Zendy

Sung-Ryong Ko | Zendy; Yukio Suzuki | Zendy; Kang-Ju Choi | Zendy; YoungHoi Kim | Zendy

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Enzymatic Preparation of Genuine Prosapogenin, 20(S)-Ginsenoside Rh₁, from Ginsenosides Re and Rg₁

Author(s) -

Sung-Ryong Ko,

Yukio Suzuki,

Kang-Ju Choi,

YoungHoi Kim

Publication year - 2000

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.64.2739

Subject(s) - ginsenoside , ginseng , saponin , chemistry , lactase , enzymatic hydrolysis , enzyme , hydrolysis , beta glucosidase , cellulase , araliaceae , biochemistry , medicine , alternative medicine , pathology

It was found that a lactase preparation from Penicillium sp. nearly quantitatively hydrolyzed ginsenosides Re and Rg1, which are major saponins in roots of Panax ginseng, to a minor saponin, 20(S)-ginsenoside Rh1 [6-O-beta-D-glucopyranosyl-20(S)-protopanaxatriol]. This is the first report on the enzymatic preparation of ginsenoside Rh1 with a high efficiency. This enzyme also readily hydrolyzed ginsenoside Rg2 to ginsenoside Rh1.

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