Glycosidic Flavonoids as Rat-Liver Injury Preventing Compounds from Green Tea | Zendy

Shingo Wada | Zendy; Puming He | Zendy; Ikue Hashimoto | Zendy; Naoharu Watanabe | Zendy; Kimio SUGIYAMA | Zendy

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Glycosidic Flavonoids as Rat-Liver Injury Preventing Compounds from Green Tea

Author(s) -

Shingo Wada,

Puming He,

Ikue Hashimoto,

Naoharu Watanabe,

Kimio SUGIYAMA

Publication year - 2000

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.64.2262

Subject(s) - glycosidic bond , flavonols , chemistry , galactosamine , glycoside , liver injury , trisaccharide , biochemistry , flavones , flavonoid , traditional medicine , pharmacology , enzyme , stereochemistry , biology , chromatography , antioxidant , medicine , glucosamine

A glycosidic flavonoids-rich fraction from green tea leaves was purified to isolate five glycosidic flavonoids, guided by the detection of a preventive effect on D-galactosamine-induced liver injury in rats. These were identified as a flavone C-glycoside (1) and trisaccharide flavonols (2-5) based on the spectroscopic analyses. These compounds suppressed the D-galactosamine-induced increase of plasma alanine aminotransferase and asparatate aminotransferase activities in rats.

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