Non-effect of Hexamethonium, a Ganglionic Blocker, on the Response of Ileal Apolipoprotein A-IV mRNA Following a Massive Small Bowel Resection in Rats | Zendy

Kei Sonoyama | Zendy; Reiko Fujiwara | Zendy; Takanori Kasai | Zendy

Open Access

Non-effect of Hexamethonium, a Ganglionic Blocker, on the Response of Ileal Apolipoprotein A-IV mRNA Following a Massive Small Bowel Resection in Rats

Author(s) -

Kei Sonoyama,

Reiko Fujiwara,

Takanori Kasai

Publication year - 2000

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.64.1282

Subject(s) - hexamethonium , ileum , medicine , endocrinology , apolipoprotein b , downregulation and upregulation , messenger rna , chemistry , receptor , gene , cholesterol , biochemistry

An intravenous infusion of hexamethonium, a ganglionic blocker, did not affect the increase in the apolipoprotein A-IV mRNA level in the residual ileum following a massive small bowel resection in unrestrained conscious rats. The result suggests that upregulation of the apolipoprotein A-IV gene in the residual ileum is not mediated by a neural pathway, including the nicotinic synapse route.

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