Cloning and Characterization of aDrosophila melanogastercDNA Encoding a Glutamate Transporter | Zendy

Tsuyoshi Kawano | Zendy; Kyoko Takuwa | Zendy; Hisato Kuniyoshi | Zendy; Naoto Juni | Zendy; Terumi Nakajima | Zendy; Daisuke Yamamoto | Zendy; Yasuo Kimura | Zendy

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Cloning and Characterization of aDrosophila melanogastercDNA Encoding a Glutamate Transporter

Author(s) -

Tsuyoshi Kawano,

Kyoko Takuwa,

Hisato Kuniyoshi,

Naoto Juni,

Terumi Nakajima,

Daisuke Yamamoto,

Yasuo Kimura

Publication year - 1999

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.63.2042

Subject(s) - drosophila melanogaster , complementary dna , xenopus , biology , cloning (programming) , glutamate receptor , transporter , excitatory amino acid transporter , microbiology and biotechnology , northern blot , amino acid , expression cloning , genetics , gene , receptor , computer science , programming language

A Drosophila cDNA encoding a glutamate transporter was cloned and examined. The predicted protein (479 amino acid residues) shows significant sequence identity with mammalian counterparts. The protein expressed in Xenopus oocytes had a glutamate transport activity. Northern blot analysis showed that the transcript increased in amount developmentally. This expression pattern is different from those of Drosophila glutamate receptors.

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