Stimulative Effect of Dietary Protein on the Phosphorylation of p70 S6 Kinase in the Skeletal Muscle and Liver of Food-deprived Rats | Zendy

Fumiaki Yoshizawa | Zendy; Taketoshi Kido | Zendy; Takashi Nagasawa | Zendy

Open Access

Stimulative Effect of Dietary Protein on the Phosphorylation of p70 S6 Kinase in the Skeletal Muscle and Liver of Food-deprived Rats

Author(s) -

Fumiaki Yoshizawa,

Taketoshi Kido,

Takashi Nagasawa

Publication year - 1999

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.63.1803

Subject(s) - phosphorylation , medicine , p70 s6 kinase 1 , endocrinology , skeletal muscle , casein , dietary protein , insulin , protein kinase a , casein kinase 2 , protein phosphorylation , biology , chemistry , biochemistry , protein kinase b , cyclin dependent kinase 2

The effect of dietary protein on p70S6k phosphorylation was examined in rats starved for 18 h and then fed either a 20% casein diet (20C) or a protein-free diet (0C). Refeeding the 20C diet, but not the 0C diet, increased p70S6k phosphorylation in both the skeletal muscle and liver. The plasma insulin concentrations were the same after refeeding the 20C or 0C diet, suggesting that a combination of dietary protein and insulin may be required to stimulate p70S6k phosphorylation.

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