Open AccessA Novel Rearranged Taxoid from Needles of the Japanese Yew,Taxus cuspidataSieb. et Zucc.
Author(s) -
Ryo Murakami,
QingWen Shi,
Tohru Horiguchi,
Takayuki Oritani
Publication year - 1999
Publication title -
bioscience biotechnology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.509
H-Index - 116
eISSN - 1347-6947
pISSN - 0916-8451
DOI - 10.1271/bbb.63.1660
Subject(s) - taxoid , taxus , stereochemistry , botany , chemistry , biology , genetics , chemotherapy , paclitaxel
Eleven taxoids were isolated from needles of the Japanese yew, Taxus cuspidata Sieb. et Zucc., one of them being a new compound whose structure was established as 5α-cinnamoyl-9α,10β,13α-triacetoxy-11(15→1)abeotaxa-4(20),11-dien-15-ol (7-deactoxytaxuspine J) on the basis of a spectroscopic analysis. Its relative stereochemistry is proposed from the results of a NOESY experiment.
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