Antimicrobial Activity of 4-Hydroxybenzoic Acid andtrans4-Hydroxycinnamic Acid Isolated and Identified from Rice Hull | Zendy

Jeong-Yong CHO | Zendy; Jae-Hak MOON | Zendy; Ki-Young Seong | Zendy; Keun-Hyung PARK | Zendy

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Antimicrobial Activity of 4-Hydroxybenzoic Acid andtrans4-Hydroxycinnamic Acid Isolated and Identified from Rice Hull

Author(s) -

Jeong-Yong CHO,

Jae-Hak MOON,

Ki-Young Seong,

Keun-Hyung PARK

Publication year - 1998

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.62.2273

Subject(s) - hydroxycinnamic acid , antimicrobial , chemistry , hydroxybenzoic acid , coumaric acid , botany , organic chemistry , biology , antioxidant

Two antimicrobial substances in rice hull were isolated and identified as 4-hydroxybenzoic acid and trans 4-hydroxycinnamic acid by LC-MS, and 1H- and 13C-NMR. An evaluation of 50% inhibition of growth (IC50) revealed that the two substances had different inhibition profiles against various microorganisms. Most of the gram-positive and some gram-negative bacteria were sensitive to trans 4-hydroxycinnamic acid and 4-hydroxybenzoic acid at IC50 concentrations of 100-170 and 160 micrograms/ml, respectively.

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