Three Antinematodal Diterpenes fromEuphorbia kansui
Author(s) -
Jian-Xiao SHI,
Zhi-Xuan LI,
Teruhiko Nitoda,
Minoru Izumi,
Hiroshi Kanzaki,
Naomichi Baba,
Kazuyoshi Kawazu,
Shûhei Nakajima
Publication year - 2007
Publication title -
bioscience biotechnology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.509
H-Index - 116
eISSN - 1347-6947
pISSN - 0916-8451
DOI - 10.1271/bbb.60677
Subject(s) - bursaphelenchus xylophilus , diterpene , nematode , terpenoid , euphorbia , traditional medicine , bioassay , stereochemistry , biology , botany , chemistry , medicine , ecology
Three compounds, 20-O-acetyl-[3-O-(2'E,4'Z)-decadienoyl]-ingenol (1), 20-O-acetyl-[5-O-(2'E,4'Z)-decadienoyl]-ingenol (2) and 3-O-(2'E,4'Z)-decadienoylingenol (3), were isolated from Euphorbia kansui under the bioassay-guided method. Each compound showed the same antinematodal activity against the nematode, Bursaphelenchus xylophilus, at a minimum effective dose (MED) of 5 microg/cotton ball.
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