PlasmaNτ-Methylhistidine Concentration Is a Sensitive Index of Myofibrillar Protein Degradation during Starvation in Rats | Zendy

Takashi Nagasawa | Zendy; Fumiaki Yoshizawa | Zendy; Naoyuki NISHIZAWA | Zendy

Open Access

PlasmaN^τ-Methylhistidine Concentration Is a Sensitive Index of Myofibrillar Protein Degradation during Starvation in Rats

Author(s) -

Takashi Nagasawa,

Fumiaki Yoshizawa,

Naoyuki NISHIZAWA

Publication year - 1996

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.60.501

Subject(s) - starvation , myofibril , incubation , medicine , endocrinology , chemistry , excretion , degradation (telecommunications) , plasma concentration , incubation period , biochemistry , biology , telecommunications , computer science

Urinary excretion of N tau-methylhistidine (MeHis) in rats was linearly elevated by starvation for 2 days. Plasma concentration of MeHis on day 1 and day 2 of starvation were increased 2.4- and 2.6-fold, respectively. The amount of released MeHis from the isolated muscles into medium during a 2-h incubation period was increased with starvation corresponded to the plasma MeHis concentration. The results of this study suggest that plasma MeHis is a sensitive index of myofibrillar protein degradation.

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