Relative Activity ofN-(β-D -Glucopyranosyl)nicotinic Acid to Nicotinic Acid as a Niacin Nutrient in Rats and inLactobacillus plantarumATCC 8014
Author(s) -
Hiroshi Nishitani,
Hiroshi Taguchi,
Michiko Yonezima,
Katsumi Shibata
Publication year - 1996
Publication title -
bioscience biotechnology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.509
H-Index - 116
eISSN - 1347-6947
pISSN - 0916-8451
DOI - 10.1271/bbb.60.333
Subject(s) - niacin , nicotinic agonist , chemistry , nicotinic acids , nutrient , lactobacillus plantarum , biochemistry , food science , lactic acid , biology , bacteria , receptor , organic chemistry , genetics
We investigated the relative activity of N-(beta-D-glucopyranosyl)-nicotinic acid as a niacin nutrient in rats and in Lactobacillus plantarum ATCC 8014. N-(beta-D-Glucopyranosyl)-nicotinic acid is a detoxified product or storage form of nicotinic acid that is found in plants. The relative activity of N-(beta-D-glucopyranosyl)nicotinic acid to nicotinic acid in rats was 1/2.3, 1/2.2, 1/1.0, and 1/1.7 as indices of the body weight gain, food intake, blood NAD content, and the increased urinary excretion of niacin and its metabolites, respectively. N-(beta-D-Glucopyranosyl)nicotinic acid had no niacin activity in Lactobacillus plantarum ATCC 8014.
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