Open AccessA New Cytotoxic Cholestane Bisdesmoside fromOrnithogalum saundersiaeBulbs
Author(s) -
Yoshihiro Mimaki,
Minpei Kuroda,
Aiko Kameyama,
Yutaka Sashida,
Toshihiko Hirano,
Kitaro Oka,
Kazuo Koike,
Tamotsu Nikaido
Publication year - 1996
Publication title -
bioscience biotechnology and biochemistry
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.509
H-Index - 116
eISSN - 1347-6947
pISSN - 0916-8451
DOI - 10.1271/bbb.60.1049
Subject(s) - cholestane , cytotoxic t cell , chemistry , fractionation , bioassay , stereochemistry , biology , biochemistry , chromatography , in vitro , ecology
Bioassay-guided fractionation of the MeOH extract of Ornithogalum saundersiae bulbs led to the isolation of a new cholestane bisdesmoside with potent cytotoxic activities toward leukemia HL-60 and MOLT-4 cells. The structure was deduced mainly from spectroscopic information.
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