Effectiveness of Green Tea Tannin on Rats with Chronic Renal Failure | Zendy

Takako Yokozawa | Zendy; Hae Young Chung | Zendy; Li He | Zendy; Hikokichi Oura | Zendy

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Effectiveness of Green Tea Tannin on Rats with Chronic Renal Failure

Author(s) -

Takako Yokozawa,

Hae Young Chung,

Li He,

Hikokichi Oura

Publication year - 1996

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.60.1000

Subject(s) - creatinine , nephrectomy , kidney , tannin , blood urea nitrogen , renal function , oxidative stress , medicine , endocrinology , urea , chemistry , biochemistry , food science

The effects of green tea tannin on nephrectomized rats were examined. There were increases in blood urea nitrogen, serum creatinine, and urinary protein, and a decrease in creatinine clearance in the nephrectomized control rats, whereas better results for these parameters were obtained in rats given green tea tannin after nephrectomy, demonstrating a suppressed progression of the renal failure. When the renal parenchyma was partially resected, the remnant kidney showed a decrease in the activity of radical scavenger enzymes. Green tea tannin, however, was found to lighten the kidney under such oxidative stress. Mesangial proliferation and glomerular sclerotic lesions, which were conspicuous in the rats that were not given green tea tannin after nephrectomy, were also relieved.

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