Dietary S-Allyl-L -cysteine Reduces Mortality with Decreased Incidence of Stroke and Behavioral Changes in Stroke-Prone Spontaneously Hypertensive Rats
Author(s) -
Jimyung Kim,
Namsoo Chang,
Won-Ki Kim,
Hyang Sook Chun
Publication year - 2006
Publication title -
bioscience biotechnology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.509
H-Index - 116
eISSN - 1347-6947
pISSN - 0916-8451
DOI - 10.1271/bbb.50697
Subject(s) - stroke (engine) , medicine , incidence (geometry) , cysteine , organosulfur compounds , anesthesia , endocrinology , chemistry , biochemistry , sulfur , organic chemistry , mechanical engineering , physics , optics , enzyme , engineering
S-Allyl-L-cysteine (SAC), an active organosulfur compound derived from garlic, was found to reduce mortality with lesser incidence of stroke and also to lower the overall stroke-related behavioral score in stroke-prone spontaneously hypertensive (SHRSP) rats by dietary administration. Consequently, the anti-stroke effect of dietary SAC was demonstrated in SHRSP rats.
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