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Non-Effect of an Antibiotic Treatment on Dietary Fiber-Induced Goblet Cell Proliferation in the Ileum of Rats
Author(s) -
Shingo Hino,
Hiroyoshi SAITA,
Tatsuya Morita
Publication year - 2013
Publication title -
bioscience biotechnology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.509
H-Index - 116
eISSN - 1347-6947
pISSN - 0916-8451
DOI - 10.1271/bbb.130241
Subject(s) - goblet cell , ileum , antibiotics , dietary fiber , cell growth , fiber , biology , microbiology and biotechnology , medicine , chemistry , endocrinology , epithelium , biochemistry , food science , genetics , organic chemistry
We examined the effect or not of an antibiotic treatment on dietary fiber-induced goblet cell proliferation in the rat ileum. The number of goblet cells in the ileum increased when rats consumed dietary fiber. However, this effect was maintained with a concurrent treatment of antibiotics, suggesting that the fiber effect on goblet cell response would remain irrespective of a bacterial component such as endotoxin.

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