Indomethacin Induction of Metamorphosis from the Asexual Stage to Sexual Stage in the Moon Jellyfish,Aurelia aurita | Zendy

Hisato Kuniyoshi | Zendy; Izumi OKUMURA | Zendy; Rie Kuroda | Zendy; Natsumi Tsujita | Zendy; Kenji Arakawa | Zendy; Jun Shoji | Zendy; Tamio Saito | Zendy; Hiroyuki Osada | Zendy

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Indomethacin Induction of Metamorphosis from the Asexual Stage to Sexual Stage in the Moon Jellyfish,Aurelia aurita

Author(s) -

Hisato Kuniyoshi,

Izumi OKUMURA,

Rie Kuroda,

Natsumi Tsujita,

Kenji Arakawa,

Jun Shoji,

Tamio Saito,

Hiroyuki Osada

Publication year - 2012

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.120076

Subject(s) - aurelia aurita , jellyfish , metamorphosis , scyphozoa , biology , asexual reproduction , nematocyst , zoology , cnidaria , larva , fishery , ecology , coral

We found while screening a chemical library that indomethacin, an inhibitor of prostaglandin biosynthesis, induced strobilation (metamorphosis from the asexual to sexual stage) in the moon jellyfish, Aurelia aurita. Indomethacin initiated strobilation in a dose-dependent manner, but was not involved in the progression of strobilation. Pharmacological experiments suggested that indomethacin could induce strobilation independently of prostaglandin biosynthesis.

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