Open AccessScreening and Identification of Disaccharides with Insulin Mimetic Activity against L6 Cells
Author(s) -
Kazuaki Yamasaki,
Ryogo Hishiki,
Eisuke Kato,
Jun Kawabata
Publication year - 2012
Publication title -
bioscience biotechnology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.509
H-Index - 116
eISSN - 1347-6947
pISSN - 0916-8451
DOI - 10.1271/bbb.110884
Subject(s) - insulin , disaccharide , diabetes mellitus , chemistry , medicine , endocrinology , biochemistry
Insulin mimetics are considered as prospective anti-diabetic agents, and the disaccharide, neohesperidose, has been found to show insulin mimetic activity against L6 cells. We screened several other disaccharides for their insulin mimetic activity and identified three new insulin mimetic disaccharides.
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