Cytotoxic Steroids from the Trunk ofBerberis koreana | Zendy

Ki Hyun Kim | Zendy; Sang Un Choi | Zendy; Chung Sub Kim | Zendy; Kang Ro Lee | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Cytotoxic Steroids from the Trunk ofBerberis koreana

Author(s) -

Ki Hyun Kim,

Sang Un Choi,

Chung Sub Kim,

Kang Ro Lee

Publication year - 2012

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.110751

Subject(s) - berberidaceae , cytotoxic t cell , stereochemistry , chemistry , trunk , steroid , ic50 , traditional medicine , biology , medicine , botany , biochemistry , in vitro , hormone

A new steroid, itesmol 3-O-palmitate (1), along with two known steroids were isolated from the trunk of Berberis koreana. The structure of 1 was determined on the basis of spectroscopic analyses involving 2D NMR and chemical reactions. Compound 1 exhibited potential antiproliferative activity against A549, SK-OV-3, SK-MEL-2, and HCT-15 cell lines (respective IC(50) values of 7.41, 9.20, 4.53, and 12.91 µM).

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research