Affinity to the Nicotinic Acetylcholine Receptor and Insecticidal Activity of Chiral Imidacloprid Derivatives with a Methylated Imidazolidine Ring | Zendy

Hisashi Nishiwaki | Zendy; Hikaru Nagaoka | Zendy; Mituhiro Kuriyama | Zendy; Satoshi Yamauchi | Zendy; Yoshihiro Shuto | Zendy

Open Access

Affinity to the Nicotinic Acetylcholine Receptor and Insecticidal Activity of Chiral Imidacloprid Derivatives with a Methylated Imidazolidine Ring

Author(s) -

Hisashi Nishiwaki,

Hikaru Nagaoka,

Mituhiro Kuriyama,

Satoshi Yamauchi,

Yoshihiro Shuto

Publication year - 2011

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.100846

Subject(s) - housefly , imidazolidine , chemistry , imidacloprid , ring (chemistry) , nicotinic acetylcholine receptor , acetylcholine receptor , nicotinic agonist , stereochemistry , musca , pharmacology , biochemistry , receptor , organic chemistry , biology , pesticide , botany , larva , agronomy

Four imidacloprid derivatives with an asymmetrically methylated imidazolidine ring were synthesized. Their affinity to the nicotinic acetylcholine receptor of housefly Musca domestica and insecticidal activity against the housefly were measured. The compound with a 5R-methylated imidazolidine ring demonstrated intrinsic activity comparable to that of the unsubstituted compound. Most of the compounds were synergized by oxygenase inhibitors.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research