Hydroxynitrile Lyases fromPrunusSeeds in the Preparation of Cyanohydrins | Zendy

Aida Solı́s | Zendy; Myrna Solís-Oba | Zendy; Herminia I. Pérez | Zendy; Norberto Manjarrez | Zendy; Julia Cassani | Zendy

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Hydroxynitrile Lyases fromPrunusSeeds in the Preparation of Cyanohydrins

Author(s) -

Aida Solı́s,

Myrna Solís-Oba,

Herminia I. Pérez,

Norberto Manjarrez,

Julia Cassani

Publication year - 2011

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.100725

Subject(s) - enantioselective synthesis , chemistry , prunus , enantiomer , aldehyde , organic chemistry , lyase , enantiomeric excess , stereochemistry , catalysis , botany , enzyme , biology

The hydroxynitrile lyase (HNL) activity of nine defatted Prunus seeds was compared for catalyzing the addition of HCN to aromatic, heteroaromatic and α,β-unsaturated aldehydes. Although the conversion and enantiomeric excess (ee) of the corresponding cyanohydrins were both influenced by the HNL source and the chemical structure of the aldehyde, Prunus HNLs were all suitable for the enantioselective preparation of cyanohydrins.

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