Antifungal Activity of Morinol B Derivatives of Tetrahydropyran Sesquilignan | Zendy

Kenta MASUDA | Zendy; Hisashi Nishiwaki | Zendy; Koichi Akiyama | Zendy; Satoshi Yamauchi | Zendy; Masafumi Maruyama | Zendy; Takuya Sugahara | Zendy; Taro Kishida | Zendy

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Antifungal Activity of Morinol B Derivatives of Tetrahydropyran Sesquilignan

Author(s) -

Kenta MASUDA,

Hisashi Nishiwaki,

Koichi Akiyama,

Satoshi Yamauchi,

Masafumi Maruyama,

Takuya Sugahara,

Taro Kishida

Publication year - 2010

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1271/bbb.100422

Subject(s) - antifungal , tetrahydropyran , stereochemistry , derivative (finance) , chemistry , biology , ring (chemistry) , organic chemistry , microbiology and biotechnology , financial economics , economics

The relationship between the structure of naturally occurring (7R,7'R,8R,8'R)-morinol B and its antifungal activity was examined. 3-Demethoxy morinol B showed much higher activity than the natural compound. The activity of the 4-butoxy-3-demethoxy derivative was higher than that of 3-demethoxy morinol B.

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