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Differential Substrate Specificity of Two Inositol Transporters ofBacillus subtilis
Author(s) -
Tetsuro Morinaga,
Takatsugu Matsuse,
Hitoshi Ashida,
Kenichi Yoshida
Publication year - 2010
Publication title -
bioscience biotechnology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.509
H-Index - 116
eISSN - 1347-6947
pISSN - 0916-8451
DOI - 10.1271/bbb.100125
Subject(s) - bacillus subtilis , inositol , transporter , substrate (aquarium) , chemistry , substrate specificity , biochemistry , biology , receptor , gene , genetics , bacteria , enzyme , ecology
Bacillus subtilis IolT is the major myo-inositol transporter for growth, while IolF is a minor one unable to support growth. We found that either IolT or IolF was sufficient for moderate growth using D-chiro-inositol. Conversely to IolT, IolF transported D-chiro-inositol more preferentially than myo-inositol. These results indicate that IolT and IolF are different in substrate specificity.

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