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Background: Professional empowerment in nursing is highly important in organizations due to its impact on the organizations themselves, patients, nurses, and the nursing discipline. However, our search revealed no instrument capable of measuring it which had been validated for Portuguese nurses. Objective: To translate, adapt and validate the Conditions of Work Effectiveness Questionnaire II (CWEQ -II). Methodology: Methodological study, with a process of translation and back-translation, using a stratified probability sample consisting of nurses from a Portuguese teaching hospital. Results: Six factors emerged factor analysis, explaining 72.925% of the total variance of the scales. Cronbach’s alpha coefficient for the factors was .85 (Opportunity), .86 (Information), .89 (Support), .797 (Resources), .81 (Formal Power) and .68 (Informal Power), and the overall value was .91. We obtained a reference value of 18.94 for structural empowerment, which is in line with other published studies. Conclusion: We translated, adapted and validated a version of the CWEQ-II for use in Portuguese nurses.

Structural empowerment in nursing: translation, adaptation and validation of the Conditions of Work Effectiveness Questionnaire II