Apolipoprotein E Expression and Behavioral Toxicity of High Charge, High Energy (HZE) Particle Radiation
Author(s) -
Yoshinori Higuchi,
Gregory A. Nelson,
Marcelo E. Vazquez,
Daniel T. Laskowitz,
James M. Slater,
Robert D. Pearlstein
Publication year - 2002
Publication title -
journal of radiation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.643
H-Index - 60
eISSN - 1349-9157
pISSN - 0449-3060
DOI - 10.1269/jrr.43.s219
Subject(s) - open field , morris water navigation task , apolipoprotein e , irradiation , toxicity , chemistry , particle radiation , knockout mouse , medicine , endocrinology , nuclear medicine , hippocampus , charged particle , physics , ion , disease , organic chemistry , nuclear physics , receptor
Apolipoprotein E (apoE) is a lipid binding protein that plays an important role in tissue repair following brain injury. In the present studies, we have investigated whether apoE affects the behavioral toxicity of high charge, high energy (HZE) particle radiation.
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