Interspecific Complementation between Mouse and Chinese Hamster Cell Mutants Hypersensitive to Ionizing Radiation. | Zendy

Koki Sato | Zendy; David J. Chen | Zendy; Kiyomi EguchiKasai | Zendy; Hiromi Itsukaichi | Zendy; Takeko Odaka | Zendy; Gary F. Strniste | Zendy

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Interspecific Complementation between Mouse and Chinese Hamster Cell Mutants Hypersensitive to Ionizing Radiation.

Author(s) -

Koki Sato,

David J. Chen,

Kiyomi EguchiKasai,

Hiromi Itsukaichi,

Takeko Odaka,

Gary F. Strniste

Publication year - 1995

Publication title -

journal of radiation research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.643

H-Index - 60

eISSN - 1349-9157

pISSN - 0449-3060

DOI - 10.1269/jrr.36.38

Subject(s) - complementation , chinese hamster , mutant , biology , hamster , ionizing radiation , cell , cell culture , genetics , microbiology and biotechnology , gene , irradiation , physics , nuclear physics

Interspecific and intraspecific hybrids were formed between mouse and Chinese hamster cell mutants hypersensitive to ionizing radiation and their radiosensitivities were examined. Chinese hamster cell mutants irs1, irs2 and irs3 and mouse mammary carcinoma cell mutants SX9 and SX10 have been found to belong to five different complementation groups. A radiosensitive mouse lymphoma cell line L5178Y-S has been demonstrated to be different from the X-ray sensitive mouse cell mutants M10 and LX830, both of which are derived from L5178Y cells, in their complementation groups. L5178Y-S is also distinct from SX9 and SX10.

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